In denial. In conflict. In love. In Treatment is set within the psychotherapy sessions of five patients. The first ever HBO half-hour drama features Paul (Gabriel Byrne), a therapist who exhibits great insight and confidence when treating his patients, but crippling insecurities while counseled by his own therapist, Gina (Dianne Wiest). Adding to his list of growing concerns, his wife, Kate (Michelle Forbes), is overcome with feelings of neglect and resent competing for his attention. Patients undergoing treatment with Paul include a young doctor (Melissa George) who has fallen in love with Paul, a Navy pilot (Blair Underwood) reevaluating his life after a failed mission in Iraq, a teenage gymnast (Mia Wasikowska) with suicidal tendencies and a passionate couple (Josh Charles and Emeth Davidtz) who are troubled in all other areas of their lives.