A marine biologist has returned with her team to a remote island in shark territorial waters where great whites come each year to give birth. The marine scientists are eager to study the biological effects of climate change on shark anatomy and behavior. What they soon discover, however, is that certain bull sharks have been radically altered by the effects of climate change. They are bolder, smarter and much more violent. The scientific mission becomes a desperate struggle to survive an onslaught of frighteningly powerful and intelligent sharks thirsty for human blood.